Academic Research Findings in Cannabis Sativa

Most medical research on marijuana is conducted on mice.  These findings suggest many hypotheses.  It is worthy to note that the majority of research conducted on mice use strictly Cannabis Sativa versus Cannabis Indica. Below you will three interesting findings.

1.  Cannabis lowers the extrapyramidal and catatonic effects of Haloperidol.   Haloperidol is potent anti-psychotic which can induce catatonia, which leaves patients unresponsive.  Extrapyramidal are drug-induced movement disorders.

2.  It is suggested that THC may be a viable drug to treat asthma.  THC causes bronchodilation.  Bronchodilation increases airway passage.

3.  Cannabis as a potential drug to treat depression and drug abuse. Known cannabinoids of Cannabis Sativa bind to two receptors, CB1, and CB2 receptor sites.  CB1 receptors are expressed in the central nervous system which the psychotropic cannabinoids bind to.  CB2 previously has been believed to be expressed in peripheral tissue and immunological tissue only, but CB2 receptors have recently been discovered in the brain. It has been observed that chronic stress-induced mice express more CB2 receptors sites than CB1 receptor sites. This suggests that CB2 receptors have a broader role in the brain than previously suspected.

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